Experts believe that they have identified a chemical in certain herbs that could help mitigate or prevent Alzheimer’s disease, but before no one runs through the species zipper, there are some catches.
In a study published in Antioxidants Magazine earlier this year, researchers at the Scripps Research Institute identified a compound called Carnosic Acid, which predominates in rosemary and sage.
The compound could be therapeutic for neurodegenerative disorders, including Alzheimer’s disease, the experts concluded.
Carnosic acid contains “antioxidant striking [and] Anti -inflammatory properties, “the researchers wrote in the findings.
Scripps Research Postdoctoral Associate Piu Bamerjee and the neurologist certified by the Board, Dr. Stuart Lipton, based in California, spoke with Fox News Digital about the results.
“In this study, we noticed that the administration of this drug in mice that had advanced the disease as Alzheimer’s significantly improved the number of neurons, as well as the number of synapses or connections between brain cells,” the team said.
The experts added: “He also reduced the inflammation caused by the current anti-amyloid antibody therapies. We also observed an improvement in the learning behavior and memory of the mice received by the drug.”
Bamerjee and Lipton also said that meatic acid is a “prodrogol”, that is, it is initially inactive, but once it enters the body, it is activated by oxidative and inflammatory stress.
“It is directed specifically to the cells subject to oxidative and inflammatory stress, without affecting healthy and healthy brain cells,” said Bamerjee.
“This makes it a safe option for therapeutics.”
Experts agreed that meatic acid could improve the inflammation that is generally produced in most aged brains.
There are precautions, however.
Courtney Kloske, director of scientific commitment for the Chicago Alzheimer’s Association, told Fox News Digital that studies based on an Alzheimer’s mouse model may be useful, but they are not conclusive.
“Models are important to help us understand the basic biology of the disease, but we need human studies in representative populations so that ideas are fully validated,” said Kloske.
“Therefore, although it is intriguing findings, more research is needed to understand the impacts and results of these compounds on people who live or at risk for Alzheimer’s.”
Cooking and rosemary will not provide full anti -inflammatory effects, Bamerjee and Lipton stressed.
“Critically, enough herbs cannot be taken to produce the same effect as our new drug,” Bamerjee said.
The study, partly funded by national health institutes, had some limitations, recognized researchers.
Kloske advised that at this time “no one should consume these herbs (or meatic acid) to prevent or treat Alzheimer’s or other cognitive impairment.”
Dr. Lee Murray, a neurologist from Jackson, Tennessee, echoed Kloske’s concerns.
“Before patients begin to incorporate rosemary and sage into all the dishes they eat, we must remember that these studies are preclinical,” Murray told Fox News Digital.
“There is currently no sufficient clinical evidence to recommend Rosemary and Sage as a standard therapy for Alzheimer’s dementia.”
Murray, however, said that the data is “encouraging” and opens the door to additional tracks for possible therapeutic.
Banerjee said he hopes that “our drug will start human clinical trials soon.”
She added: “If it is effective, it will be a great drug for those who suffer from Alzheimer’s … From the results of our animal studies, we are cautiously optimistic for their success in human clinical trials.”
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